European project Spacetime, Spatial Analysis of Cancer Evolution in the Tumour Immune Microenvironment
Project coordinator: STICHTING AMSTERDAM UMC
Coordinator for NIB: dr. Barbara Breznik, dr. Metka Novak
Code: HORIZON.2.1 – Health, HORIZON Research and Innovation Actions
Duration: 1 August 2024 – 31 July 2029
Website: https://cordis.europa.eu/project/id/101136552
The SPACETIME project covers this mission by gathering knowledge on the development of the lung cancer microenvironment, over the next 5 years. The tumor microenvironment is the complex of cancerous cells, immune cells and other supporting cells that are present within tumors. The composition of this microenvironment can be a determinant of the response to the therapy, such as immune therapy. To better understand the development of this very complex composition, the partners within the SPACETIME consortium will use technologically advanced methods to analyze biopsies from lung cancer patients from early stage through to late-stage disease, as well as samples from relevant animal models of these disease stages. The data acquired will be processed using computer models to extract recurring patterns. These patterns will then be tested for their relevance in certain types of cancer treatment. This type of research is only possible through close collaboration of many researchers from various scientific backgrounds, which has been established within the SPACETIME consortium. The ultimate goal of the project is to develop knowledge that will enable physicians to predict which treatment will have the best chance of effectivity for each patient.