Services and Products
- AGRICULTURE INDUSTRY SERVICES
- PHARMACEUTICAL AND BIOTECHNOLOGY INDUSTRY SERVICES
- ENVIRONMENTAL MONITORING AND WATER-QUALITY TESTING SERVICES
- TRAINING AND RELATED SERVICES
- MUTAGENICITY ANALYSIS under GLP
- Detection of Genetically Modified Organisms (GMO)
- Detection of microorganisms – plant pathogens
- Toxicology studies for agrochemicals and biocides
- In vitro genotoxicity testing of agrochemicals and biocides (Ames assay, micronucelus assay, Comet assay, γ-H2AX assay)
- Ecotoxicity studies and biomonitoring (aquatic and terrestrial)
- Testing the quality of surface water and aquatic sediments (organic pollution due to agricultural activities)
- Recombinant protein expression in plants
- Activity assessment of antimicrobial substances
- Determination of microbial community composition using molecular techniques in different samples
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- Systems biology studies of production cell lines (characterization, biomarkers search, production process optimization, production risk reduction)
- Nucleic acid detection and quantification, residual DNA detection
- Molecular detection and quantification of target organisms and viruses
- Concentration and purification of viruses, phages and VLPs
- Cell based assays for activity and toxicity evaluation
- Cell migration/invasion and adhesion assays
- In vitro genotoxicity testing (Ames assay, SOS/umuC assay, micronucelus assay, Comet assay, γ-H2AX assay)
- In vitro toxicity studies (cytotoxicity, apoptosis, mitochondrial activity, oxidative stress, cell cycle analysis, toxicological gene regulation)
- Biocompatibility assessment of medical devices
- Evaluation of micronuclei formation and DNA damage in blood and exfoliated epithelial cells (clinical studies, human biomonitoring)
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- Validation of water treatment plants (WTP) efficiency (measuring the BOD, COD, microbial activity and community analysis, toxicity and genotoxicity of WTP effluents)
- Validation of water purification methods (inactivation and removal methods, filters efficiency (toxicology and microbiology, including viruses)
- Concentration and detection of waterborne viruses
- Water analyses (physiochemichal parameters, cyanotoxins, biological analyses of: viruses, phytobenthos, phytoplankton and zooplankton, ecotoxicology testing on algae, cyanobacteria and zebrafish embryos)
- Cytotoxicity and genotoxicity testing of un-concentrated and concentrated water samples (Ames assay, SOS/umuC assay, Comet assay, micronucelus assay)
- Consulting investors in the developmental planning within protected areas
- Consulting and production of nature conservation plans for selected terrestrial and freshwater animal groups Environmental fate studies
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- GMO and plant pathogens: hands on training, consulting and technical auditing, organization of inter-laboratory testing
- Development of protocols and workflows compliant with ISO/IEC 17025 and ISO 9001
- Organization of workshops in cooperation with spin-off company BioSistemika Ltd.
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On the NIB we have certified GLP laboratory for testing mutagenicity with bacterial reverse mutation assay, or the Ames test (OECD 471). Testing is performed in accordance with the OECD Principles of Good Laboratory Practice (GLP) in various strains of Salmonella typhimurium (TA97a, TA98, TA100, TA102, TA1535, TA1537, TA1538 et al.) and Escherichia coli (WP2 uvrA, WP2 uvrA pKM101) with/without metabolic activation. Price of one GLP study is between 1500 and 4500 €, the time required to carry out the study is 4-6 weeks.
We also provide other toxicological tests in vitro under the "non-DLP" conditions:
• SOS / umuC test (ISO 13829: 2000) in bacteria
• In vitro micronucleus test on mammalian cells (OECD 487)
• Comet assay
• Analysis of the γ-H2Ax by flow cytometry
• Test HepG2CDKN1A-DsRed
• Testing the cytotoxicity of medical devices (ISO 10993-5 and ISO 10993-12)
• Consulting and support
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: +386 59232861, +386 59232862
Fax: +386 5 9232715
We also provide other toxicological tests in vitro under the "non-DLP" conditions:
• SOS / umuC test (ISO 13829: 2000) in bacteria
• In vitro micronucleus test on mammalian cells (OECD 487)
• Comet assay
• Analysis of the γ-H2Ax by flow cytometry
• Test HepG2CDKN1A-DsRed
• Testing the cytotoxicity of medical devices (ISO 10993-5 and ISO 10993-12)
• Consulting and support
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: +386 59232861, +386 59232862
Fax: +386 5 9232715
